Journal Articles
1. An
Internal Fluorescent Probe of G-quadruplex Folding and Energy Transfer
Anaelle Dumas, Nathan W.
Luedtke, 2010, In review.
2. Label-free detection of
nucleic acids by turn-ON and turn-OFF G-quadruplex-mediated fluorescence
Jiangtao Ren, Haixia Qin, Jiahai
Wang, Nathan W. Luedtke, Erkang Wang,
2010, In review.
3.
pH-Mediated fluorescence
and G-quadruplex binding of amido phthalocyanines
J. Alzeer, N. W.
Luedtke, Biochemistry, 2010, 49,
4339.
4.
Multiple-turnover
isotopic labeling of Fmoc- and Boc-protected amino acids with oxygen isotopes
M. S. Seyfried, B. S. Lauber, N.
W. Luedtke, Org. Lett., 2010,
12, 104.
5.
Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRAS
G-quadruplexes
M. Paramasivam, A. Membrino, S. Cogoi, J.
Alzeer, N. W. Luedtke, L. E. Xodo, Chem. Commun.,
2010,
625.
6.
Guanidino phthalocyanines as high affinity G-quadruplex fluorescent probes and
transcriptional regulators
J. Alzeer, B. R. Vummidi, P. J. C.
Roth, N. W. Luedtke,
Angew. Chem. Intl. Ed.,
2009,
9362. (English)(German)
7.
An
efficient two-step synthesis of metal-free phthalocyanines using a zinc(II)
template
J. Alzeer, P. J. C. Roth,
N. W. Luedtke, Chem. Commun.,
2009,
1970.
8. Targeting G-quadruplex DNA with Small Molecules
N. W. Luedtke,
Chimia.
2009,
63, 134.
9.
Surveying polypeptide and protein domain conformation and association with
FlAsH and ReAsH
N. W. Luedtke, R.
J. Dexter, D. B. Fired, A. Schepartz, Nat. Chem. Biol.
2007, 779.
10.
Lanthanide-mediated phosphoester hydrolysis and phosphate elimination from
phosphopeptides
N. W. Luedtke, A.
Schepartz, Chem. Commun.
2005, 5426.
11.
A
rapid library screen for tailoring beta-peptide structure and function
J. A. Kritzer, N. W. Luedtke, E. A.
Harker, A. Schepartz, J. Am. Chem. Soc. 2005, 14584.
12.
On the electronic structure of ethidium
N. W. Luedtke, Q. Liu, Y. Tor,
Chem. Eur. J. 2005, 495.
13.
Chemical biology: innovative solutions for diverse challenges
J. A. Kritzer, N. W. Luedtke,
Chem. Biol. 2005, 617.
14.
RNA-selective modification by a platinum(II) complex conjugated to amino- and
guanidinoglycosides
J. Boer, K. F. Blount, N. W. Luedtke, L. Elson-Schwab, Y. Tor, Angew.
Chem. Intl. Ed. 2005, 927.
15.
Symmetrical dinuclear complexes based on [Ru(dpq)2(phen)]2+
with high DNA affinity
J. Aldrich-Wright, C. Brodie, E. C. Glazer, N. W.
Luedtke, Y. Tor, Chem. Commun. 2004, 1018.
16.
Affinity and specificity of aminoglycoside dimers and acridine conjugates to the
HIV-1 Rev response element
N. W. Luedtke, Q. Liu, Y. Tor, Biochemistry, 2003, 11391.
17.
Cellular
uptake of aminoglycosides, guanidinoglycosides, and poly-arginine
N. W. Luedtke, P. Carmichael, Y. Tor, J. Am.
Chem. Soc., 2003, 12374.
18.
Fluorescence-based methods for evaluating the RNA affinity and specificity of
HIV-1 Rev-RRE inhibitors
N. W. Luedtke, Y. Tor, Biopolymers,
2003, 103.
19.
The
DNA and RNA specificity of eilatin Ru(II) complexes as compared to eilatin and
ethidium
N. W. Luedtke, J. S. Hwang, E. C. Glazer, D. Gut,
M. Kol, Y. Tor, Nucleic Acids Res., 2003, 5732.
20.
Synthesis, photophysical properties, and nucleic acid binding of
phenanthridinium derivatives
of ethidium
N. W. Luedtke, Q. Liu, Y.
Tor, Bioorg. Med. Chem., 2003, 5235.
21.
Inhibition of nuclear import mediated by the Rev-arginine rich motif by RNA
molecules
K. Fineberg, T. Fineberg, A. Graessmann, N. Luedtke, Y. Tor, D. Jans, A.
Loyter, Biochemistry, 2003, 2625.
22.
Eilatin
Ru(II) complexes display anti-HIV activity and enantiomeric diversity in the
binding of RNA
N. W. Luedtke, J. S. Hwang, E. C. Glazer, D. Gut,
M. Kol, Y. Tor, Chembiochem, 2002, 766.
23.
2-Aminopurine
as a real-time probe of enzymatic cleavage and inhibition of hammerhead
ribozymes
S. R. Kirk, N. W. Luedtke, Y. Tor, Bioorg.
Med. Chem., 2001, 2295.
24.
A
simple conversion of amines into monosubstituted ureas in organic and aqueous
solvents
Q. Liu, N. W. Luedtke, Y. Tor, Tetrahedron
Lett., 2001, 1445.
25.
Development of a functional backbone cyclic mimetic of the HIV-1 Tat
arginine-rich motif
A. Friedler, D. Friedler, N. W. Luedtke, Y. Tor, A. Loyter, C. Gilon,
J. Biol. Chem., 2000, 23783.
26. Guanidinoglycosides:
A novel family of RNA ligands
N. W. Luedtke, T. J. Baker, M. Goodman, Y. Tor, J.
Am. Chem. Soc., 2000, 12035.
27.
A
novel solid-phase assembly for identifying potent and selective RNA ligands
N. W. Luedtke, Y. Tor,
Angew. Chem. Intl. Ed., 2000, 1788.
28.
Neomycin-acridine conjugate: A potent inhibitor of Rev-RRE binding
S. R. Kirk, N. W. Luedtke, Y. Tor, J. Am.
Chem. Soc., 2000, 980.
29.
Synthesis and anti-HIV activity of guanidinoglycosides
T. J. Baker, N. W. Luedtke, Y. Tor, M. Goodman,
J. Org. Chem., 2000, 9054.
30. The
5'-GNC preference for mustard cross-linking is preserved in a restriction
fragment
J. T. Millard, N. W. Luedtke, R. J. Spencer, Anti-Cancer Drug Des.,
1996, 485.
Book
Chapter
1.
Targeting HIV RNA with Small Molecules. In: DNA
and RNA Binders Vol. 1
N.
W. Luedtke, Y. Tor, 2002, Wiley-VCH, 18-40.
Patents
1.
Preparation and uses of
guanidinium-modified
porphyrins and phthalocyanines
N. W. Luedtke, J. Alzeer, B. R. Vummidi, 2010,
WO/2010/028780.
2. 8- and 6,8-substituted 2'-deoxyguanosines and uses
thereof
N. W. Luedtke and A. Dumas, 2010, WO/2010/028781.
3. Preparation of phenanthridine
derivatives as anti-viral agents
Y. Tor and N. W. Luedtke, 2005, WO/2005/016343.
4.
Guanidinium
derivatives for improved cellular transport
Y.
Tor and N. W. Luedtke, 2005, WO/2005/025513.
5.
Guanidinylation,
guanidinoglycosides, uses, and methods of assaying their
activity
M. Goodman,
Y. Tor, T. Baker, and N. W. Luedtke, 2003, U.S. 6,525,182 and 6,833,445.
Doctoral Thesis
RNA Affinity and Specificity of Modified Aminoglycosides,
Metal Complexes, and Intercalating Agents
N. W. Luedtke
PhD Thesis, University of California, San Diego, 2003.
Diplom Thesis
Synthesis and Evaluation of Guanidino
Phthalocyanines for G-quadruplex Binding
Phillipe J. C. Roth, Institute of Organic Chemistry, University of Zurich, 2008.